CAS No.65515-32-4 | Methyl 6-chloro-2-methoxynicotinate
Name: Methyl 6-chloro-2-methoxynicotinate CAS No.65515-32-4 MF: C8H8ClNO3 MW: 201.61 Purity:97% Package: 5g,25g,100g,500g,1kg,25kg Worldwide Delivery
Categories：
Analytical Chemicals
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Product introduction
Introduction and application of CAS No.65515-32-4 | Methyl 6-chloro-2-methoxynicotinate
Methyl 6-chloro-2-methoxynicotinate is a coupling agent that has been used in the synthesis of mineralocorticoid receptor antagonists. It is a functionalized molecule with an oxime group, which allows for the formation of new bonds by reaction with nucleophiles such as hydroxide ion or alcohols. This compound can be synthesized using the Miyaura cross-coupling reaction and Suzuki coupling reactions.
These reactions are scalable and chemoselective, making them suitable for large scale production. The compounds have also been shown to be effective as antagonists against mineralocorticoid receptors, which may lead to potential therapeutic uses.
Synonyms:
3-Pyridinecarboxylic acid, 6-chloro-2-methoxy-, methyl ester;
methyl 6-chloro-2-methoxynicotinate;
Methyl 6-chloro-2-methoxypyridine-3-carboxylate;
2-chloro-6-methoxy-nicotinic acid methyl este
Specification of CAS No.65515-32-4 | Methyl 6-chloro-2-methoxynicotinate
|
ITEMS |
SPECIFICATION |
|
CAS No. |
65515-32-4 |
|
MF |
C8H8ClNO3 |
|
MW |
201.61 |
|
Boiling point |
262.0±35.0 °C(Predicted) |
|
Density |
1.288±0.06 g/cm3(Predicted) |
|
acidity coefficient(pKa) |
-1.81±0.10(Predicted) |
Package of CAS No.65515-32-4 | Methyl 6-chloro-2-methoxynicotinate
Package:100g; 500g; 1kg; 25kg;bulk package
Transportation: by courier/ by air/ by sea
Related Articles of CAS No.65515-32-4 | Methyl 6-chloro-2-methoxynicotinate
Synthesis and cross coupling of a highly substituted 2-pyridylboronate: application to the large scale synthesis of a mineralocorticoid antagonist
C Boos, DM Bowles, C Cai, A Casimiro-Garcia… - Tetrahedron letters, 2011 - Elsevier
… Preparation of methyl 2-methoxy-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)nicotinate
8 A mixture of methyl 6-chloro-2-methoxynicotinate 11 (94.0 g, 0.47 mol), bis(pinacolato) …
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